Transmission Dynamics

Researching AMR transmission dynamics at the human-animal-environmental interface in different agricultural systems

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To better understand AMR risks due to antimicrobial use in agriculture, aquaculture and livestock, we undertake studies in selected sites into the biology, ecology, and epidemiology of infections. We use latest available technologies, such as whole genome sequencing to characterise movement of AMR genes within these ecologies and investigate drivers of AMR emergence and transmission at the human-animal-environmental interface. In addition, we conduct research on AMR occurrence and residues in food items. 

 

Our main activities are:

  1. Agree and promote use of adequate study designs following epidemiological principles for genotyping research and AMR transmission dynamics studies at the human-livestock-environment interface
  2. Generate evidence on the extent of antimicrobial-resistant bacteria and antimicrobial residues found in livestock, fish, humans, the environment, water and food; 
  3. Understand the transmission and genetic mechanisms of resistance in agriculture and the implications for human and animal health; and 
  4. Develop a range of mathematical and biological models of AMR in low- and middle-income countries to understand the relative contribution of agriculturally-associated AMR to the human AMR burden and risk of drug-resistant infections in different contexts.

 

The case studies featured below illustrate ongoing and past research and provide insights into how AMR research is done within the CGIAR AMR hub.