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Using phages to replace antibiotics and reduce drug-resistant non-typhoidal Salmonella in poultry farms in Kenya

The goal of this project is to investigate bacteriophage-based solutions to kill Salmonella strains isolated from poultry farms in Kenya.

The project collects Salmonella samples from poultry farms and slaughterhouses in Kenya and types strains for antibiotic resistance genes.

Known bacteriophages are then tested for their capacity to disintegrate selected Salmonella strains, and new bacteriophages with lytic activity towards Salmonella strains isolated.

Researchers then test combinations of bacteriophages in a Salmonella infection model in chickens, conduct field trials using bacteriophages in selected smallholder farms, and assess the impact of bacteriophage technology and adoption by women chicken farmers.

The project includes new commercial products that are alternatives to antibiotics for the prevention and control of infections that could be adopted by the poultry industry in Kenya.